Verification of protein structures

Protein structures might contain errors independently if they have been created from experimental information or from modeling. Therefore it is necessary to have some possibility to check for errors in a given model independent on how this model was created. The methods used to predict the structure of a protein can be divided into two groups, depending on if they are use physicochemical information or statistical information.

Procheck

Procheck is a program that checks the geometry of a protein structure. The following checks are made:

1. Covalent geometry
2. Planarity
3. Dihedral angles
4. Chirality
5. Non-bonded interactions
6. Main-chain hydrogen bonds
7. Disulphide bonds
8. Stereochemical parameters
9. Parameter comparisons
10. Residue-by-residue analysis

WhatIf